*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : UK7894000
CHEMICAL NAME           : Prosta-5,13-dien-1-oic acid,
                          11,15-dihydroxy-16,16-dimethyl-9-oxo-,
                          (5Z,11-alpha,13E,15R)-
CAS REGISTRY NUMBER     : 39746-25-3
BEILSTEIN REFERENCE NO. : 2896843
LAST UPDATED            : 199612
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C22-H36-O5
MOLECULAR WEIGHT        : 380.58
COMPOUND DESCRIPTOR     : Reproductive Effector
                          Human
SYNONYMS/TRADE NAMES :
   *   (5Z,11-alpha,13E,15R)-11,15-Dihydroxy-16,16-dimethyl-9-oxoprosta-5,13-di
     en-1-oic acid
   *   7-(2-(4,4-Dimethyl-3-hydroxy-1-octenyl)-3-hydroxy-5-oxocyclopentyl)-5-he
     ptenoic acid
   * 16,16-Dimethyl-pge2
   * 16,16-Dimethyl-prostaglandin E2
   * 5-Heptenoic acid,  
   7-(2-(4,4-dimethyl-3-hydroxy-1-octenyl)-3-hydroxy-5-oxocyclopentyl)-
 
                       *** HEALTH HAZARD DATA ***
 
                          ** REPRODUCTIVE DATA **
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Human - woman
DOSE                    : 4 ug/kg
SEX/DURATION            : female 34 week(s) after conception
TOXIC EFFECTS :
   Reproductive - Fertility - abortion
   Reproductive - Effects on Embryo or Fetus - fetal death
REFERENCE :
   PRGLBA Prostaglandins.  (Geron-X, Inc., P.O. Box 1108, Los Altos, CA 94022)
   V.1-    1972-  Volume(issue)/page/year: 6,349,1974
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Intravaginal
SPECIES OBSERVED        : Human - woman
DOSE                    : 64 ug/kg
SEX/DURATION            : female 6 week(s) after conception
TOXIC EFFECTS :
   Reproductive - Fertility - abortion
REFERENCE :
   CCPTAY Contraception.  (Geron-X, Inc., POB 1108, Los Altos, CA 94022)  V.1-
   1970-  Volume(issue)/page/year: 16,167,1977
 
                            *** END OF RECORD ***