*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : UI3340000
CHEMICAL NAME           : Propylamine, 1-methoxy-N-nitroso-N-propyl-
CAS REGISTRY NUMBER     : 53230-00-5
LAST UPDATED            : 199203
DATA ITEMS CITED        : 2
WISWESSER LINE NOTATION : ONN3&Y2&O1
COMPOUND DESCRIPTOR     : Tumorigen
SYNONYMS/TRADE NAMES :
   * alpha-Dipropylnitrosamine methyl ether
   * 1-Methoxypropylpropylnitrosamin
   * 1-Methoxypropylpropylnitrosamine
   * 1-Mppn
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - hamster
DOSE/DURATION           : 458 mg/kg
TOXIC EFFECTS :
   Blood - hemorrhage
REFERENCE :
   ZKKOBW Zeitschrift fuer Krebsforschung und Klinische Onkologie.  (Berlin,
   Fed. Rep. Ger.)  V.76-92, 1971-78.  For publisher information, see JCROD7.
   Volume(issue)/page/year: 90,215,1977
 
                          ** TUMORIGENIC DATA **
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - hamster
DOSE/DURATION           : 555 mg/kg/37W-I
TOXIC EFFECTS :
   Tumorigenic - neoplastic by RTECS criteria
   Lungs, Thorax, or Respiration - tumors
   Gastrointestinal - tumors
REFERENCE :
   ZKKOBW Zeitschrift fuer Krebsforschung und Klinische Onkologie.  (Berlin,
   Fed. Rep. Ger.)  V.76-92, 1971-78.  For publisher information, see JCROD7.
   Volume(issue)/page/year: 90,215,1977
 
                            *** END OF RECORD ***