*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : UI0185000
CHEMICAL NAME           : 1-Propylamine, 2-chloro-N,N-bis(2-chloroethyl)-,
                          hydrochloride
CAS REGISTRY NUMBER     : 1936-40-9
LAST UPDATED            : 198606
DATA ITEMS CITED        : 4
MOLECULAR FORMULA       : C7-H14-Cl3-N.Cl-H
MOLECULAR WEIGHT        : 255.03
WISWESSER LINE NOTATION : GY1&1N2G2G &GH
COMPOUND DESCRIPTOR     : Drug
                          Mutagen
SYNONYMS/TRADE NAMES :
   * Bis(beta-chloroethyl)-beta-chloropropylamine hydrochloride
   * N,N-Bis(2-chloroethyl)-2-chloropropylamine hydrochloride
   * 2-Chloro-N,N-bis(2-chloroethyl)-1-propylamine hydrochloride
   * Embichin 7
   * Novembichin
   * Novembikhin
   * Novoembichin
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 300 ug/kg
TOXIC EFFECTS :
   Tumorigenic - active as anti-cancer agent
REFERENCE :
   CPBTAL Chemical and Pharmaceutical Bulletin.  (Japan Pub. Trading Co., USA,
   1255 Howard St., San Francisco, CA 94103)  V.6-    1958-
   Volume(issue)/page/year: 8,807,1960
 
TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 25 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   NTIS** National Technical Information Service.  (Springfield, VA 22161)
   Formerly U.S. Clearinghouse for Scientific & Technical Information.
   Volume(issue)/page/year: PB158-507
 
                            ** MUTATION DATA **
 
TYPE OF TEST            : DNA inhibition
TEST SYSTEM             : Rodent - mouse Ascites tumor
DOSE/DURATION           : 30 mg/L
REFERENCE :
   NEOLA4 Neoplasma.  (Karger-Libri, P.O. Box, CH-4009 Basel, Switzerland) V.4-
      1957-  Volume(issue)/page/year: 22,105,1975
 
TYPE OF TEST            : Mutation test systems - not otherwise specified
TEST SYSTEM             : Rodent - mouse Ascites tumor
DOSE/DURATION           : 30 mg/L
REFERENCE :
   NEOLA4 Neoplasma.  (Karger-Libri, P.O. Box, CH-4009 Basel, Switzerland) V.4-
      1957-  Volume(issue)/page/year: 22,105,1975
 
                            *** END OF RECORD ***