*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : UH4428500
CHEMICAL NAME           : Propiophenone,
                          3-(4-(o-tolyl)piperazinyl)-3',4',5'-trimethoxy-,
                          hydrochloride
CAS REGISTRY NUMBER     : 16785-26-5
LAST UPDATED            : 199007
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C23-H30-N2-O4.Cl-H
MOLECULAR WEIGHT        : 435.01
WISWESSER LINE NOTATION : T6N DNTJ A2VR CO1 DO1 EO1& DR B1 &GH
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * Piperazine, 1-(o-tolyl)-4-(3,4,5-trimethoxybenzoylethyl)-, hydrochloride
   * 3-(4-(o-Tolyl)piperazinyl)-3',4',5'-trimethoxypropiophenone hydrochloride
   * 1-(beta-(3,4,5-Trimethoxybenzoyl)ethyl)-4-(o-tolyl)piperazine  
   monohydrochloride
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 540 mg/kg
TOXIC EFFECTS :
   Brain and Coverings - recordings from specific areas of CNS
   Behavioral - somnolence (general depressed activity)
   Behavioral - changes in motor activity (specific assay)
REFERENCE :
   JMCMAR Journal of Medicinal Chemistry.  (American Chemical Soc.,
   Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC
   20037)  V.6-    1963-  Volume(issue)/page/year: 12,865,1969
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 340 mg/kg
TOXIC EFFECTS :
   Behavioral - somnolence (general depressed activity)
REFERENCE :
   JMCMAR Journal of Medicinal Chemistry.  (American Chemical Soc.,
   Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC
   20037)  V.6-    1963-  Volume(issue)/page/year: 11,332,1968
 
                            *** END OF RECORD ***