*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : UH2470000
CHEMICAL NAME           : Propiophenone,
                          3-((beta-hydroxy-alpha-methylphenethyl)amino)-3'-meth
                          oxy-, hydrochloride, d,l-
CAS REGISTRY NUMBER     : 14223-94-0
LAST UPDATED            : 199012
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C19-H23-N-O3.Cl-H
MOLECULAR WEIGHT        : 349.89
WISWESSER LINE NOTATION : 1YR&YQM2VR CO1 &GH
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * d,l-3-(beta-Hydroxy-alpha-methyl-phenethylamino)-3'-methoxypropiophenone, 
    hydrochloride
   * Myophedrine
   * 1-Propanone,  
   3-((2-hydroxy-1-methyl-2-phenylethyl)amino)-1-(3-methoxyphenyl)-, HCl,  
   d,l-
   * d,l-Oxyphedrine
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 1200 mg/kg
TOXIC EFFECTS :
   Behavioral - convulsions or effect on seizure threshold
   Lungs, Thorax, or Respiration - other changes
REFERENCE :
   RPTOAN Russian Pharmacology and Toxicology (English Translation).
   Translation of FATOAO.  (Euromed Pub., 33, Woodlands Rd., Surbiton, Surrey,
   UK)  V.30-    1967-  Volume(issue)/page/year: 38,199,1975
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 34 mg/kg
TOXIC EFFECTS :
   Behavioral - convulsions or effect on seizure threshold
   Lungs, Thorax, or Respiration - other changes
REFERENCE :
   RPTOAN Russian Pharmacology and Toxicology (English Translation).
   Translation of FATOAO.  (Euromed Pub., 33, Woodlands Rd., Surbiton, Surrey,
   UK)  V.30-    1967-  Volume(issue)/page/year: 38,199,1975
 
                            *** END OF RECORD ***