*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : UG5760000
CHEMICAL NAME           : o-Propionotoluidide, 2-(propylamino)-
CAS REGISTRY NUMBER     : 721-50-6
BEILSTEIN REFERENCE NO. : 2108498
LAST UPDATED            : 199706
DATA ITEMS CITED        : 3
MOLECULAR FORMULA       : C13-H20-N2-O
MOLECULAR WEIGHT        : 220.35
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * Astra 1512
   * Astra 1515
   * Citanest
   * L 67
   * o-Methyl-alpha-propylaminopropionanilide
   * N-(2-Methylphenyl)-2-(propylamino)propanamide
   * Prilocaine
   * Propanamide, N-(2-methylphenyl)-2-(propylamino)-
   * Propitocaine
   * alpha-n-Propylamino-2-methylpropionanilide
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 231 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   NYKZAU Nippon Yakurigaku Zasshi.  Japanese Journal of Pharmacology. (Nippon
   Yakuri Gakkai, c/o Kyoto Daigaku Igakubu Yakurigaku Kyoshitsu, Konoe-cho,
   Yoshida, Sakyo-ku, Kyoto 606, Japan) V.40-    1944- Volume(issue)/page/year:
   61,455,1965
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 519 mg/kg
TOXIC EFFECTS :
   Behavioral - excitement
   Lungs, Thorax, or Respiration - dyspnea
   Skin and Appendages - hair
REFERENCE :
   NYKZAU Nippon Yakurigaku Zasshi.  Japanese Journal of Pharmacology. (Nippon
   Yakuri Gakkai, c/o Kyoto Daigaku Igakubu Yakurigaku Kyoshitsu, Konoe-cho,
   Yoshida, Sakyo-ku, Kyoto 606, Japan) V.40-    1944- Volume(issue)/page/year:
   61,455,1965
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 59900 ug/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   NYKZAU Nippon Yakurigaku Zasshi.  Japanese Journal of Pharmacology. (Nippon
   Yakuri Gakkai, c/o Kyoto Daigaku Igakubu Yakurigaku Kyoshitsu, Konoe-cho,
   Yoshida, Sakyo-ku, Kyoto 606, Japan) V.40-    1944- Volume(issue)/page/year:
   61,455,1965
 
                            *** END OF RECORD ***