*** CHEMICAL IDENTIFICATION ***
RTECS NUMBER : UF8225000
CHEMICAL NAME : Propionic acid, 2-(2,4,5-trichlorophenoxy)-
CAS REGISTRY NUMBER : 93-72-1
BEILSTEIN REFERENCE NO. : 1985768
REFERENCE : 3-06-00-00721 (Beilstein Handbook Reference)
LAST UPDATED : 199710
DATA ITEMS CITED : 13
MOLECULAR FORMULA : C9-H7-Cl3-O3
MOLECULAR WEIGHT : 269.51
WISWESSER LINE NOTATION : QVY1&OR BG DG EG
COMPOUND DESCRIPTOR : Agricultural Chemical
Tumorigen
Reproductive Effector
SYNONYMS/TRADE NAMES :
* Acide 2-(2,4,5-trichloro-phenoxy) propionique
* Acido 2-(2,4,5-tricloro-fenossi)-propionico
* Amchem 2,4,5-TP
* Aqua-vex
* Color-set
* Double strength
* Fenoprop
* Fenormone
* Fruitone T
* Kurosal G
* Kurosal SL
* Kwas 2,4,5-trojchlorofenoksypropionowy
* Kyselina 2-(2,4,5-trichlorfenoxy)propionova
* Miller Nu Set
* Propon
* RCRA waste number U233
* Silvex
* Silvi-Rhap
* Sta-Fast
* 2,4,5-TC
* 2,4,5-TCPPA
* 2,4,5-TP
* 2-(2,4,5-Trichloor-fenoxy)-propionzuur
* alpha-(2,4,5-Trichlorophenoxy)propionic acid
* 2-(2,4,5-Trichlorophenoxy)propionic acid
* 2,4,5-Trichlorophenoxy-alpha-propionic acid
* 2-(2,4,5-Trichlor-phenoxy)-propionsaeure
* Weed-B-gon
*** HEALTH HAZARD DATA ***
** ACUTE TOXICITY DATA **
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Oral
SPECIES OBSERVED : Rodent - rat
DOSE/DURATION : 650 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
RREVAH Residue Reviews. (Springer-Verlag New York, Inc., Service Center, 44
Hartz Way, Secaucus, NJ 07094) V.1- 1962- Volume(issue)/page/year:
10,97,1965
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Oral
SPECIES OBSERVED : Rodent - mouse
DOSE/DURATION : 276 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
RPZHAW Roczniki Panstwowego Zakladu Higieny. (Ars Polona, POB 1001, 00-068
Warsaw 1, Poland) V.1- 1950- Volume(issue)/page/year: 31,373,1980
TYPE OF TEST : LD - Lethal dose
ROUTE OF EXPOSURE : Intraperitoneal
SPECIES OBSERVED : Rodent - mouse
DOSE/DURATION : >250 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
ANTCAO Antibiotics and Chemotherapy (Washington, DC). (Washington, DC)
V.1-12, 1951-62. For publisher information, see CLMEA3.
Volume(issue)/page/year: 9,715,1959
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Administration onto the skin
SPECIES OBSERVED : Rodent - rabbit
DOSE/DURATION : >3200 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
PEMNDP Pesticide Manual. (The British Crop Protection Council, 20 Bridport
Rd., Thornton Heath CR4 7QG, UK) V.1- 1968- Volume(issue)/page/year:
8,376,1987
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Oral
SPECIES OBSERVED : Mammal - species unspecified
DOSE/DURATION : 650 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
SCIEAS Science. (American Assoc. for the Advancement of Science, 1333 H
St., NW, Washington, DC 20005) V.1- 1895- Volume(issue)/page/year:
165,465,1969
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Unreported
SPECIES OBSERVED : Mammal - species unspecified
DOSE/DURATION : 650 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
30ZDA9 "Chemistry of Pesticides," Melnikov, N.N., New York, Springer-Verlag
New York, Inc., 1971 Volume(issue)/page/year: -,173,1971
** REPRODUCTIVE DATA **
TYPE OF TEST : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE : Oral
SPECIES OBSERVED : Rodent - mouse
DOSE : 1617 mg/kg
SEX/DURATION : female 12-15 day(s) after conception
TOXIC EFFECTS :
Reproductive - Effects on Embryo or Fetus - fetotoxicity (except death,
e.g., stunted fetus)
Reproductive - Specific Developmental Abnormalities - craniofacial
(including nose and tongue)
REFERENCE :
AECTCV Archives of Environmental Contamination and Toxicology.
(Springer-Verlag New York, Inc., Service Center, 44 Hartz Way, Secaucus, NJ
070944) V.1- 1973- Volume(issue)/page/year: 6,33,1977
TYPE OF TEST : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE : Subcutaneous
SPECIES OBSERVED : Rodent - mouse
DOSE : 1617 mg/kg
SEX/DURATION : female 12-15 day(s) after conception
TOXIC EFFECTS :
Reproductive - Effects on Embryo or Fetus - fetotoxicity (except death,
e.g., stunted fetus)
Reproductive - Effects on Embryo or Fetus - fetal death
Reproductive - Specific Developmental Abnormalities - craniofacial
(including nose and tongue)
REFERENCE :
AECTCV Archives of Environmental Contamination and Toxicology.
(Springer-Verlag New York, Inc., Service Center, 44 Hartz Way, Secaucus, NJ
070944) V.1- 1973- Volume(issue)/page/year: 6,33,1977
*** REVIEWS ***
IARC Cancer Review:Human Limited Evidence
IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals
to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210)
V.1- 1972- Volume(issue)/page/year: 41,357,1986
*** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA ***
NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA :
NOHS - National Occupational Hazard Survey (1974)
NOHS Hazard Code - 84581
No. of Facilities: 32 (estimated)
No. of Industries: 1
No. of Occupations: 1
No. of Employees: 65 (estimated)
*** STATUS IN U.S. ***
EPA TSCA Section 8(d) unpublished health/safety studies
On EPA IRIS database
EPA TSCA TEST SUBMISSION (TSCATS) DATA BASE, JUNE 1998
*** END OF RECORD ***