*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : UC3900000
CHEMICAL NAME           : 2-Propanone, triphenylphosphoranylidene-
CAS REGISTRY NUMBER     : 1439-36-7
BEILSTEIN REFERENCE NO. : 0750077
REFERENCE               : 4-16-00-00977 (Beilstein Handbook Reference)
LAST UPDATED            : 199612
DATA ITEMS CITED        : 3
MOLECULAR FORMULA       : C21-H19-O-P
MOLECULAR WEIGHT        : 318.37
WISWESSER LINE NOTATION : 1V1UPR&R&R
SYNONYMS/TRADE NAMES :
   * Triphenylphosphoranylidene-2-propanone
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 32 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   CSLNX* U.S. Army Armament Research & Development Command, Chemical Systems
   Laboratory, NIOSH Exchange Chemicals.  (Aberdeen Proving Ground, MD 21010)
   Volume(issue)/page/year: NX#01327
 
                 ** OTHER MULTIPLE DOSE TOXICITY DATA **
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 520 mg/kg/30D-I
TOXIC EFFECTS :
   Gastrointestinal - ulceration or bleeding from stomach
   Blood - normocytic anemia
   Biochemical - Enzyme inhibition, induction, or change in blood or tissue
   levels - transaminases
REFERENCE :
   KSRNAM Kiso to Rinsho.  Clinical Report.  (Yubunsha Co., Ltd., 1-5, Kanda
   Suda-Cho, Chiyoda-ku, KS Bldg., Tokyo 101, Japan)  V.1-    1960-
   Volume(issue)/page/year: 9,2641,1975
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 1560 mg/kg/26W-I
TOXIC EFFECTS :
   Blood - changes in cell count (unspecified)
   Blood - changes in spleen
   Biochemical - Metabolism (Intermediary) - other proteins
REFERENCE :
   KSRNAM Kiso to Rinsho.  Clinical Report.  (Yubunsha Co., Ltd., 1-5, Kanda
   Suda-Cho, Chiyoda-ku, KS Bldg., Tokyo 101, Japan)  V.1-    1960-
   Volume(issue)/page/year: 9,2641,1975
 
                            *** END OF RECORD ***