*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : UC1934050
CHEMICAL NAME           : 1-Propanone,
                          1-(10-(3-(dimethylamino)propyl)phenothiazin-2-yl)-
CAS REGISTRY NUMBER     : 3568-24-9
LAST UPDATED            : 198910
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C20-H24-N2-O-S
MOLECULAR WEIGHT        : 340.52
WISWESSER LINE NOTATION : T C666 BN ISJ B3N1&1 MV2
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * BAY 188
   * Bayer 188
   * 1497CB
   * Combelen
   * Combilen
   * 1-(10-(3-(Dimethylamino)propyl)phenothiazin-2-yl)-1-propanone
   * 1-Propanone, 1-(10-(3-(dimethylamino)propyl)-10H-phenothiazin-2-yl)-
   * Propionpromazine
   * 3-Propionyl-10-(3'-dimethylaminopropyl)phenothiazin
   * Propionylpromazine
   * 2-Propionylpromazine
   * Propionylpromazone
   * Propiopromazine
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 500 mg/kg
TOXIC EFFECTS :
   Behavioral - convulsions or effect on seizure threshold
REFERENCE :
   AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans
   Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium)  V.4-   
   1898-  Volume(issue)/page/year: 115,1,1958
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 67 mg/kg
TOXIC EFFECTS :
   Behavioral - convulsions or effect on seizure threshold
REFERENCE :
   AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans
   Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium)  V.4-   
   1898-  Volume(issue)/page/year: 115,1,1958
 
                            *** END OF RECORD ***