*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : UC0728000
CHEMICAL NAME           : 2-Propanone,
                          3-chloro-1-(6,7-dimethoxy-1-isoquinolinyl)-1-(3,4-dim
                          ethoxyphenyl)-
CAS REGISTRY NUMBER     : 66170-03-4
LAST UPDATED            : 198510
DATA ITEMS CITED        : 1
MOLECULAR FORMULA       : C22-H22-Cl-N-O5
MOLECULAR WEIGHT        : 415.90
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   *   3-Chloro-1-(6,7-dimethoxy-1-isoquinolinyl)-1-(3,4-dimethoxyphenyl)-2-pro
     panone
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 130 mg/kg
TOXIC EFFECTS :
   Autonomic Nervous System - smooth muscle relaxant (mechanism undefined,
   spasmolytic)
   Cardiac - other changes
REFERENCE :
   DANTAL Doklady Akademii Nauk Tadzhikskoi SSR.  Proceedings of the Academy of
   Sciences of the Tadzhik SSR.  (V/O Mezhdunarodnaya Kniga, 113095 Moscow,
   USSR)  No.1-22, 1951-57; V.1-    1958-  Volume(issue)/page/year:
   20(11),33,1977
 
                            *** END OF RECORD ***