*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : UC0522500
CHEMICAL NAME           : 2-Propanone,
                          1,3-bis(4-(3-(trifluoromethyl)phenyl)-1-piperazinyl)-
                          , dihydrochloride, hydrate
CAS REGISTRY NUMBER     : 67931-94-6
LAST UPDATED            : 199606
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C25-H28-F6-N4-O.2Cl-H.H2-O
MOLECULAR WEIGHT        : 604.50
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * 1,3-Bis(4-(m-(trifluoromethyl)phenyl)piperazino)-propan-2-one  
   dihydrochloride hydrate
   * 1,3-Bis(4-(3-(trifluoromethyl)phenyl)-1-piperazinyl)-2-propanone  
   dihydrochloride hydrate
   * LJ 1163
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 180 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   USXXAM United States Patent Document.  (U.S. Patent Office, Box 9,
   Washington, DC 20231)  Volume(issue)/page/year: #4203986
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 18 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   USXXAM United States Patent Document.  (U.S. Patent Office, Box 9,
   Washington, DC 20231)  Volume(issue)/page/year: #4203986
 
                            *** END OF RECORD ***