*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : UC0300000
CHEMICAL NAME           : 1-Propanone,
                          1-(3-acetyl-4-(2-hydroxy-3-(4-hydroxy-4-phenyl-1-pipe
                          ridinyl)propoxy)pheny l)-
CAS REGISTRY NUMBER     : 79010-25-6
BEILSTEIN REFERENCE NO. : 4593340
LAST UPDATED            : 199612
DATA ITEMS CITED        : 1
MOLECULAR FORMULA       : C25-H31-N-O5
MOLECULAR WEIGHT        : 425.57
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   *   1-(3-Acetyl-4-(2-hydroxy-3-(4-hydroxy-4-phenyl-1-piperidinyl)propoxy)phe
     nyl)-1-propanone
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 681 mg/kg
TOXIC EFFECTS :
   Behavioral - somnolence (general depressed activity)
   Vascular - BP lowering not characterized in autonomic section
REFERENCE :
   IJSBDB Indian Journal of Chemistry, Section B: Organic Chemistry, Including
   Medicinal Chemistry. (Publications & Information Directorate, Council of
   Scientific and Industrial Research (CSIR), Hillside Rd., New Delhi 110 012,
   India)  V.14B-    1976-  Volume(issue)/page/year: 20,480,1981
 
                            *** END OF RECORD ***