*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : UB1460800
CHEMICAL NAME           : 2-Propanol,
                          1-(2,5-dichlorophenoxy)-3-((1,1-dimethylethyl)amino)-
                          , hydrochloride
CAS REGISTRY NUMBER     : 54247-25-5
LAST UPDATED            : 199412
DATA ITEMS CITED        : 4
MOLECULAR FORMULA       : C13-H19-Cl2-N-O2.Cl-H
MOLECULAR WEIGHT        : 328.69
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * Chlorpropanol hydrochloride
   * Cloranolol hydrochloride
   * 1-(2,5-Dichlorophenoxy)-3-(tert-butylamino)-2-propanol hydrochloride
   * 1-(2,5-Dichlorophenoxy)-3-((1,1-dimethylethyl)amino)-2-propanol  
   hydrochloride
   * 1-(2,5-Diclorofenoxi)-3-(tert-butilamino)-2-propanol clorhidrato
   * GYKI-41099
   * Tobanum
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 1300 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   MDACAP Medicamentos de Actualidad.  (J.R. Prous, S.A., Apartado de Correos
   540, 08080 Barcelona, Spain)  V.1-    1965-  Volume(issue)/page/year:
   21,529,1985
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 25 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   MDACAP Medicamentos de Actualidad.  (J.R. Prous, S.A., Apartado de Correos
   540, 08080 Barcelona, Spain)  V.1-    1965-  Volume(issue)/page/year:
   21,529,1985
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 450 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   MDACAP Medicamentos de Actualidad.  (J.R. Prous, S.A., Apartado de Correos
   540, 08080 Barcelona, Spain)  V.1-    1965-  Volume(issue)/page/year:
   21,529,1985
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 35 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   MDACAP Medicamentos de Actualidad.  (J.R. Prous, S.A., Apartado de Correos
   540, 08080 Barcelona, Spain)  V.1-    1965-  Volume(issue)/page/year:
   21,529,1985
 
                            *** END OF RECORD ***