*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : UA7252000
CHEMICAL NAME           : 2-Propanol,
                          1-(1,2-benzisothiazol-4-yloxy)-3-tert-butylamino-
CAS REGISTRY NUMBER     : 68524-74-3
BEILSTEIN REFERENCE NO. : 1218930
LAST UPDATED            : 199612
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C14-H20-N2-O2-S
MOLECULAR WEIGHT        : 280.42
WISWESSER LINE NOTATION : T56 BSNJ FO1YQ1MX1&1&1
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * 1-(1,2-Benzisothiazol-4-yloxy)-3-tert-butylamino-2-propanol
   * LU 24938
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 340 mg/kg
TOXIC EFFECTS :
   Autonomic Nervous System - beta-adrenergic blockage
REFERENCE :
   ARZNAD Arzneimittel-Forschung. Drug Research.  (Editio Cantor Verlag,
   Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.)  V.1-    1951-
   Volume(issue)/page/year: 30,1831,1980
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 154 mg/kg
TOXIC EFFECTS :
   Autonomic Nervous System - beta-adrenergic blockage
REFERENCE :
   ARZNAD Arzneimittel-Forschung. Drug Research.  (Editio Cantor Verlag,
   Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.)  V.1-    1951-
   Volume(issue)/page/year: 30,1831,1980
 
                            *** END OF RECORD ***