*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : TZ4850000
CHEMICAL NAME           : Propanenitrile,
                          2-(beta-D-glucopyranosyloxy)-2-methyl-
CAS REGISTRY NUMBER     : 554-35-8
BEILSTEIN REFERENCE NO. : 0019237
REFERENCE               : 5-17-07-00397 (Beilstein Handbook Reference)
LAST UPDATED            : 199612
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C10-H17-N-O6
MOLECULAR WEIGHT        : 247.28
WISWESSER LINE NOTATION : T6OTJ BQ CQ DQ EQ FOX1&1&1CN
COMPOUND DESCRIPTOR     : Reproductive Effector
SYNONYMS/TRADE NAMES :
   * 2-(beta-D-Glucopyranosyloxy)isobutyronitrile
   * 2-(beta-D-Glucopyranosyloxy)-2-methylpropanenitrile
   * Linamarin
   * Phaseolunatin
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 500 mg/kg
TOXIC EFFECTS :
   Sense Organs and Special Senses (Eye) - effect, not otherwise specified
   Peripheral Nerve and Sensation - flaccid paralysis without anesthesia
   (usually neuromuscular blockage)
   Gastrointestinal - hypermotility, diarrhea
REFERENCE :
   TXAPA9 Toxicology and Applied Pharmacology.  (Academic Press, Inc., 1 E.
   First St., Duluth, MN 55802) V.1-    1959-  Volume(issue)/page/year:
   42,539,1977
 
                          ** REPRODUCTIVE DATA **
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - hamster
DOSE                    : 120 mg/kg
SEX/DURATION            : female 8 day(s) after conception
TOXIC EFFECTS :
   Reproductive - Specific Developmental Abnormalities - musculoskeletal system
REFERENCE :
   TJADAB Teratology, The International Journal of Abnormal Development. (Alan
   R. Liss, Inc., 41 E. 11th St., New York, NY 10003)  V.1-    1968-
   Volume(issue)/page/year: 31,241,1985
 
                            *** END OF RECORD ***