*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : TY3192800
CHEMICAL NAME           : 1,3-Propanediol,
                          2-((4,6-bis(1-aziridinyl)-s-triazin-2-yl)amino)-2-met
                          hyl-
CAS REGISTRY NUMBER     : 60819-42-3
BEILSTEIN REFERENCE NO. : 0554214
LAST UPDATED            : 199612
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C11-H18-N6-O2
MOLECULAR WEIGHT        : 266.35
WISWESSER LINE NOTATION : T6N CN ENJ BMX1&1Q1Q D- AT3NTJ& F- AT3NTJ
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * 2-((4,6-Bis(1-aziridinyl)-s-triazin-2-yl)amino)-2-methyl-1,3-propanediol
   *   2-((4,6-Bis(1-aziridinyl)-1,3,5-triazin-2-yl)amino)-2-methyl-1,3-propane
     diol
   * 2-(4,6-Diaziridinyl-2-s-triazinylamino)-2-methyl-1,3-propanediol
   * 6-(1-(1,2-Dihydroxymethyl)ethylamino)-2,4-di(ethyleneimino)triazine
   * 1,3-Propanediol, 2-(4,6-diaziridinyl-2-s-triazinylamino)-2-methyl-
   * s-Triazine, 2,4-diaziridinyl-6-(1,3-dihydroxy-2-methyl-2-propylamino)-
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 8 mg/kg
TOXIC EFFECTS :
   Tumorigenic - active as anti-cancer agent
REFERENCE :
   VOONAW Voprosy Onkologii.  Problems of Oncology.  For English translation,
   see PONCAU. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR)  V.1-10,
   1928-37; V.1-    1955-  Volume(issue)/page/year: 23(12),70,1977
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 13 mg/kg
TOXIC EFFECTS :
   Tumorigenic - active as anti-cancer agent
REFERENCE :
   PCJOAU Pharmaceutical Chemistry Journal (English Translation).  Translation
   of KHFZAN. (Plenum Pub. Corp., 233 Spring St., New York, NY 10013)  No.1-
   1967-  Volume(issue)/page/year: 12,481,1978
 
                            *** END OF RECORD ***