*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : TZ3150000
CHEMICAL NAME           : Propane, 1,3-epoxy-2,2-dimethyl-
CAS REGISTRY NUMBER     : 6921-35-3
BEILSTEIN REFERENCE NO. : 0102430
REFERENCE               : 5-17-01-00085 (Beilstein Handbook Reference)
LAST UPDATED            : 199612
DATA ITEMS CITED        : 3
MOLECULAR FORMULA       : C5-H10-O
MOLECULAR WEIGHT        : 86.15
WISWESSER LINE NOTATION : T4OTJ C1 C1
COMPOUND DESCRIPTOR     : Tumorigen
                          Drug
SYNONYMS/TRADE NAMES :
   * 3,3-Dimethyloxetane
   * beta,beta-Dimethyltrimethylene oxide
   * 3,3-Dimethyltrimethylene oxide
   * 1,3-Epoxy-2,2-dimethylpropane
   * Oxetane, 3,3-dimethyl-
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 2 gm/kg
TOXIC EFFECTS :
   Behavioral - general anesthetic
REFERENCE :
   JMPCAS Journal of Medicinal and Pharmaceutical Chemistry.  (Washington, DC)
   V.1-5, 1959-62.  For publisher information, see JMCMAR.
   Volume(issue)/page/year: 1,355,1959
 
                          ** TUMORIGENIC DATA **
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 1020 mg/kg/61W-I
TOXIC EFFECTS :
   Tumorigenic - equivocal tumorigenic agent by RTECS criteria
   Tumorigenic - tumors at site of application
REFERENCE :
   BJCAAI British Journal of Cancer.  (Macmillan Press Ltd., Houndmills,
   Basingstoke, Hants. RG21 2XS, UK)  V.1-    1947-  Volume(issue)/page/year:
   17,100,1963

                              *** REVIEWS ***
 
   TOXICOLOGY REVIEW
   22HAAD "Microbial Toxins, 1970-72," Ajil, S.J., et al., eds., New York,
   Academic Press, Inc., 1970-72  Volume(issue)/page/year: 6,409,1971

 
                            *** END OF RECORD ***