*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : TY6678000
CHEMICAL NAME           : 1,2-Propanediol,
                          3-((10-ethyl-11-(p-hydroxyphenyl)dibenz(b,f)oxepin-3-
                          yl)oxy)-, hydrate (4:1)
CAS REGISTRY NUMBER     : 85850-93-7
LAST UPDATED            : 199712
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C25-H24-O5.1/4H2-O
MOLECULAR WEIGHT        : 408.95
WISWESSER LINE NOTATION : T C676 BOJ EO1YQ1Q IR DQ& J2 &QH 1/4
COMPOUND DESCRIPTOR     : Reproductive Effector
SYNONYMS/TRADE NAMES :
   *   3-((10-Ethyl-11-(p-hydroxyphenyl)dibenz(b,f)oxepin-3-yl)oxy)-1,2-propane
     diol hydrate (4:1)
 
                       *** HEALTH HAZARD DATA ***
 
                          ** REPRODUCTIVE DATA **
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE                    : 25 mg/kg
SEX/DURATION            : female 4 day(s) after conception
TOXIC EFFECTS :
   Reproductive - Fertility - pre-implantation mortality (e.g. reduction in
   number of implants per female; total number of implants per corpora lutea)
REFERENCE :
   JMCMAR Journal of Medicinal Chemistry.  (American Chemical Soc.,
   Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC
   20037)  V.6-    1963-  Volume(issue)/page/year: 26,1131,1983
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE                    : 30 mg/kg
SEX/DURATION            : female 3 day(s) pre-mating
TOXIC EFFECTS :
   Reproductive - Maternal Effects - uterus, cervix, vagina
REFERENCE :
   JMCMAR Journal of Medicinal Chemistry.  (American Chemical Soc.,
   Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC
   20037)  V.6-    1963-  Volume(issue)/page/year: 26,1131,1983
 
                            *** END OF RECORD ***