*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : TY3850000
CHEMICAL NAME           : 1,3-Propanediol, 2-sec-butyl-2-methyl-, dicarbamate
CAS REGISTRY NUMBER     : 64-55-1
BEILSTEIN REFERENCE NO. : 1788226
REFERENCE               : 4-03-00-00074 (Beilstein Handbook Reference)
LAST UPDATED            : 199612
DATA ITEMS CITED        : 5
MOLECULAR FORMULA       : C10-H20-N2-O4
MOLECULAR WEIGHT        : 232.32
WISWESSER LINE NOTATION : ZVO1X1&1OVZY2&1
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * Axiten
   * Butatensin
   * 2-sec-Butyl-2-methyl-1,3-propanediol dicarbamate
   * 2-sec-Butyl-2-methyltrimethylene dicarbamate
   * Capla
   * Carbamic acid, 2-sec-butyl-, 2-methyltrimethylene ester
   * Carbuten
   * Dicamoylmethtane
   * 2,2-Dicarbamyloxymethyl-3-methylpentane
   * Dormate
   * Ipotensivo
   * Mebutamate
   * Mebutina
   * MEGA
   * 2-Methyl-2-sec-butyl-1,3-propanediol dicarbamate
   * 2-Methyl-2-(1-methylpropyl)-1,3-propanediol dicarbamate
   * NO-Press
   * Prean
   * Sigmafon
   * Vallene
   * W 583
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 1160 mg/kg
TOXIC EFFECTS :
   Behavioral - somnolence (general depressed activity)
   Lungs, Thorax, or Respiration - other changes
REFERENCE :
   JPETAB Journal of Pharmacology and Experimental Therapeutics.  (Williams &
   Wilkins Co., 428 E. Preston St., Baltimore, MD 21202)  V.1-    1909/10-
   Volume(issue)/page/year: 134,356,1961
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 410 mg/kg
TOXIC EFFECTS :
   Behavioral - somnolence (general depressed activity)
   Lungs, Thorax, or Respiration - other changes
REFERENCE :
   JPETAB Journal of Pharmacology and Experimental Therapeutics.  (Williams &
   Wilkins Co., 428 E. Preston St., Baltimore, MD 21202)  V.1-    1909/10-
   Volume(issue)/page/year: 134,356,1961
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 550 mg/kg
TOXIC EFFECTS :
   Behavioral - somnolence (general depressed activity)
   Lungs, Thorax, or Respiration - other changes
REFERENCE :
   JPETAB Journal of Pharmacology and Experimental Therapeutics.  (Williams &
   Wilkins Co., 428 E. Preston St., Baltimore, MD 21202)  V.1-    1909/10-
   Volume(issue)/page/year: 134,356,1961
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 460 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   JMCMAR Journal of Medicinal Chemistry.  (American Chemical Soc.,
   Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC
   20037)  V.6-    1963-  Volume(issue)/page/year: 12,462,1969
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Bird - wild bird species
DOSE/DURATION           : 100 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   TXAPA9 Toxicology and Applied Pharmacology.  (Academic Press, Inc., 1 E.
   First St., Duluth, MN 55802) V.1-    1959-  Volume(issue)/page/year:
   21,315,1972
 
                            *** END OF RECORD ***