*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : TX7085000
CHEMICAL NAME           : 1,3-Propanediamine,
                          N-(2-chloroethyl)-N'-(2-methoxy-9-acridinyl)-,
                          dihydrochloride
CAS REGISTRY NUMBER     : 38915-08-1
LAST UPDATED            : 199410
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C19-H22-Cl-N3-O.2Cl-H
MOLECULAR WEIGHT        : 416.81
WISWESSER LINE NOTATION : T C666 BNJ DO1 IM3M2G &GH 2 &QH 1/2
COMPOUND DESCRIPTOR     : Drug
                          Mutagen
SYNONYMS/TRADE NAMES :
   * Acridine, 9-((3-((2-chloroethyl)amino)propyl)amino)-2-methoxy-,  
   dihydrochloride
   * 9-((3-((2-Chloroethyl)amino)propyl)amino)-2-methoxyacridine  
   dihydrochloride
   * ICR 376
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD20 - Lethal Dose
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 25 mg/kg
TOXIC EFFECTS :
   Tumorigenic - active as anti-cancer agent
REFERENCE :
   JMCMAR Journal of Medicinal Chemistry.  (American Chemical Soc.,
   Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC
   20037)  V.6-    1963-  Volume(issue)/page/year: 15,739,1972
 
                            ** MUTATION DATA **
 
TYPE OF TEST            : Mutation in microorganisms
TEST SYSTEM             : Bacteria - Salmonella typhimurium
DOSE/DURATION           : 5 ug/plate
REFERENCE :
   JMCMAR Journal of Medicinal Chemistry.  (American Chemical Soc.,
   Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC
   20037)  V.6-    1963-  Volume(issue)/page/year: 15,739,1972
 
                            *** END OF RECORD ***