*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : TX7082000
CHEMICAL NAME           : 1,3-Propanediamine,
                          N-(2-chloroethyl)-N-ethyl-N'-(1,2,3,4-tetrahydro-9-ac
                          ridinyl)-, dihydrochloride, hemihydrate
CAS REGISTRY NUMBER     : 78218-20-9
LAST UPDATED            : 199410
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C20-H28-Cl-N3.2Cl-H.1/2H2-O
MOLECULAR WEIGHT        : 427.84
WISWESSER LINE NOTATION : T C666 BN&&TJ IM3N2&2G &GH 2 &QH 1/2
COMPOUND DESCRIPTOR     : Mutagen
SYNONYMS/TRADE NAMES :
   * ICR 360
   * 1,2,3,4-Tetrahydro-9-((3-((2-chloroethyl)ethylamino)propyl)amino)acridine 
    2HCl hemihydrate
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD20 - Lethal Dose
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 6418 ug/kg
TOXIC EFFECTS :
   Tumorigenic - active as anti-cancer agent
REFERENCE :
   JMCMAR Journal of Medicinal Chemistry.  (American Chemical Soc.,
   Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC
   20037)  V.6-    1963-  Volume(issue)/page/year: 15,739,1972
 
                            ** MUTATION DATA **
 
TYPE OF TEST            : Mutation in microorganisms
TEST SYSTEM             : Bacteria - Salmonella typhimurium
DOSE/DURATION           : 2500 ng/plate
REFERENCE :
   MUREAV Mutation Research.  (Elsevier Science Pub. B.V., POB 211, 1000 AE
   Amsterdam, Netherlands) V.1-    1964-  Volume(issue)/page/year: 136,185,1984
 
                            *** END OF RECORD ***