*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : TX7019000
CHEMICAL NAME           : 1,3-Propanediamine,
                          N,N-bis(2-chloroethyl)-N'-(2-methoxy-9-acridinyl)-,
                          dihydrochloride, hemihydrate
CAS REGISTRY NUMBER     : 78232-12-9
LAST UPDATED            : 199012
DATA ITEMS CITED        : 1
MOLECULAR FORMULA       : C21-H25-Cl2-N3-O.2Cl-H.1/2H2-O
MOLECULAR WEIGHT        : 451.82
WISWESSER LINE NOTATION : T C666 BNJ FO1 IM3N2G2G &GH 2 &QH 1/2
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * Acridine, 9-((3-(bis(2-chloroethyl)amino)propyl)amino)-2-methoxy-, 2HCl  
   hemihydrate
   * 9-((3-(Bis(2-chloroethyl)amino)propyl)amino)-2-methoxyacridine  
   dihydrochloride hemihydrate
   * ICR 230
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD20 - Lethal Dose
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 4518 ug/kg
TOXIC EFFECTS :
   Tumorigenic - active as anti-cancer agent
REFERENCE :
   JMCMAR Journal of Medicinal Chemistry.  (American Chemical Soc.,
   Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC
   20037)  V.6-    1963-  Volume(issue)/page/year: 15,739,1972
 
                            *** END OF RECORD ***