*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : TX7006000
CHEMICAL NAME           : 1,3-Propanediamine,
                          N-benzo(b)(1,10)phenanthrolin-7-yl-N'-(2-chloroethyl)
                          -, dihydrochloride
CAS REGISTRY NUMBER     : 38915-58-1
LAST UPDATED            : 199410
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C21-H21-Cl-N4.2Cl-H
MOLECULAR WEIGHT        : 437.83
WISWESSER LINE NOTATION : T D6 B666 CN RNJ JM3M2G &GH 2
COMPOUND DESCRIPTOR     : Drug
                          Mutagen
SYNONYMS/TRADE NAMES :
   * Benzo(b)(1,10)phenanthroline, 7-((3-((2-chloroethyl)amino)propyl)amino)-, 
    dihydrochloride
   * 7-((3-((2-Chloroethyl)amino)propyl)amino)benzo(b)(1,10)phenanthroline  
   dihydrochloride
   * ICR 395
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD20 - Lethal Dose
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 18 mg/kg
TOXIC EFFECTS :
   Tumorigenic - active as anti-cancer agent
REFERENCE :
   JMCMAR Journal of Medicinal Chemistry.  (American Chemical Soc.,
   Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC
   20037)  V.6-    1963-  Volume(issue)/page/year: 15,739,1972
 
                            ** MUTATION DATA **
 
TYPE OF TEST            : Mutation in microorganisms
TEST SYSTEM             : Bacteria - Salmonella typhimurium
DOSE/DURATION           : 500 ng/plate
REFERENCE :
   MUREAV Mutation Research.  (Elsevier Science Pub. B.V., POB 211, 1000 AE
   Amsterdam, Netherlands) V.1-    1964-  Volume(issue)/page/year: 136,185,1984
 
                            *** END OF RECORD ***