*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : TX1628750
CHEMICAL NAME           : 2-Propanamine,
                          N-(1-methylethyl)-N-(2-((6-((1-methyl-4-piperidinyl)o
                          xy)-5-(methylthio)-
                          2-(4-morpholinyl)-4-pyrimidinyl)oxy)ethyl)-,
                          hydrobromide, hydrate (1:2:2)
CAS REGISTRY NUMBER     : 57259-22-0
LAST UPDATED            : 199703
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C23-H41-N5-O3-S.2Br-H.2H2-O
MOLECULAR WEIGHT        : 664.62
COMPOUND DESCRIPTOR     : Drug
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 800 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   GWXXBX German Offenlegungsschrift Patent Document.  (U.S. Patent and
   Trademark Office, Foreign Patents, Washington, DC 20231)
   Volume(issue)/page/year: #2503136
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 50 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   GWXXBX German Offenlegungsschrift Patent Document.  (U.S. Patent and
   Trademark Office, Foreign Patents, Washington, DC 20231)
   Volume(issue)/page/year: #2503136
 
                            *** END OF RECORD ***