*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : TX1459250
CHEMICAL NAME           : Propanamide,
                          N-(1,3,4,6,7,11b-hexahydro-2H-benzo(a)quinolizin-2-yl
                          )-N-phenyl-, monohydrochloride, trans-
CAS REGISTRY NUMBER     : 56682-31-6
LAST UPDATED            : 199212
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C22-H26-N2-O.Cl-H
MOLECULAR WEIGHT        : 370.96
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * N-(1,3,4,6,7,11b-Hexahydro-benzo(a)quinolizin-2-yl)propionanilide  
   hydrochloride
   * TR 2379
 
                       *** HEALTH HAZARD DATA ***
 
                 ** OTHER MULTIPLE DOSE TOXICITY DATA **
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 74620 mg/kg/13W-I
TOXIC EFFECTS :
   Liver - changes in liver weight
   Kidney, Ureter, Bladder - changes in bladder weight
   Related to Chronic Data - death
REFERENCE :
   TXCYAC Toxicology.  (Elsevier Scientific Pub. Ireland, Ltd., POB 85,
   Limerick, Ireland) V.1-    1973-  Volume(issue)/page/year: 4,215,1975
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Mammal - dog
DOSE/DURATION           : 14560 mg/kg/13W-I
TOXIC EFFECTS :
   Behavioral - food intake (animal)
   Nutritional and Gross Metabolic - weight loss or decreased weight gain
   Related to Chronic Data - death
REFERENCE :
   TXCYAC Toxicology.  (Elsevier Scientific Pub. Ireland, Ltd., POB 85,
   Limerick, Ireland) V.1-    1973-  Volume(issue)/page/year: 4,215,1975
 
                            *** END OF RECORD ***