*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : TW3589200
CHEMICAL NAME           : Proline,
                          1-(2-((bis(1-aziridinyl)phosphinyl)amino)-6-chloro-4-
                          pyrimidinyl)-, ethyl ester
LAST UPDATED            : 199207
DATA ITEMS CITED        : 1
MOLECULAR FORMULA       : C15-H22-Cl-N6-O3-P
MOLECULAR WEIGHT        : 400.85
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * 1-(2-((Bis(1-aziridinyl)phosphinyl)amino)-6-chloro-4-pyrimidinyl)proline  
   ethyl ester
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD - Lethal dose
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : >500 mg/kg
TOXIC EFFECTS :
   Tumorigenic - active as anti-cancer agent
REFERENCE :
   FATOAO Farmakologiya i Toksikologiya (Moscow).  For English translation, see
   PHTXA6 and RPTOAN. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.2-   
   1939-  Volume(issue)/page/year: 28,340,1965
 
                            *** END OF RECORD ***