*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : OK6493000
CHEMICAL NAME           : L-Prolinamide, N(sup
                          2)-((phenylmethoxy)carbonyl)-L-glutaminyl-L-tryptophy
                          l-L-seryl-L-
                          tyrosyl-D-methionyl-L-leucyl-L-arginyl-N-ethyl-,
                          hydrochloride, hydrate (1:1:2)
CAS REGISTRY NUMBER     : 71033-66-4
LAST UPDATED            : 199803
DATA ITEMS CITED        : 1
MOLECULAR FORMULA       : C60-H84-N14-O13-S.Cl-H.2H2-O
MOLECULAR WEIGHT        : 1314.14
COMPOUND DESCRIPTOR     : Reproductive Effector
                          Hormone
SYNONYMS/TRADE NAMES :
   * Z-(Gln(sup 1)-des-His(sup 2)-D-Met(sup 6)-des-Gly(sup 10))-LHRH  
   ethylamide HCl H2-O (1:1:2)
 
                       *** HEALTH HAZARD DATA ***
 
                          ** REPRODUCTIVE DATA **
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - rat
DOSE                    : 90 mg/kg
SEX/DURATION            : female 1 day(s) pre-mating
TOXIC EFFECTS :
   Reproductive - Fertility - other measures of fertility
REFERENCE :
   JMCMAR Journal of Medicinal Chemistry.  (American Chemical Soc.,
   Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC
   20037)  V.6-    1963-  Volume(issue)/page/year: 22,935,1979
 
                            *** END OF RECORD ***