*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : TW3578500
CHEMICAL NAME           : L-Prolinamide,
                          L-histidyl-N-(1-methyl-2-phenylethyl)-5-oxo-L-prolyl-
CAS REGISTRY NUMBER     : 67543-15-1
BEILSTEIN REFERENCE NO. : 0951665
LAST UPDATED            : 199612
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C25-H32-N6-O4
MOLECULAR WEIGHT        : 480.63
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * L-Histidyl-N-(1-methyl-2-phenylethyl)-5-oxo-L-prolyl-L-prolinamide
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 1200 mg/kg
TOXIC EFFECTS :
   Nutritional and Gross Metabolic - body temperature increase
REFERENCE :
   EJMCA5 European Journal of Medicinal Chemistry--Chimie Therapeutique.
   (Editions Scientifiques Elsevier, 29 rue Buffon, F-75005, Paris, France)
   V.9-    1974-  Volume(issue)/page/year: 14,425,1979
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 380 mg/kg
TOXIC EFFECTS :
   Nutritional and Gross Metabolic - body temperature increase
REFERENCE :
   EJMCA5 European Journal of Medicinal Chemistry--Chimie Therapeutique.
   (Editions Scientifiques Elsevier, 29 rue Buffon, F-75005, Paris, France)
   V.9-    1974-  Volume(issue)/page/year: 14,425,1979
 
                            *** END OF RECORD ***