*** CHEMICAL IDENTIFICATION ***
RTECS NUMBER : TU5548000
CHEMICAL NAME : Pregn-5-en-20-one, 3-beta,17-dihydroxy-
CAS REGISTRY NUMBER : 387-79-1
LAST UPDATED : 198910
DATA ITEMS CITED : 2
MOLECULAR FORMULA : C21-H32-O3
MOLECULAR WEIGHT : 332.53
WISWESSER LINE NOTATION : L E5 B666 LUTJ A1 E1 FV1 FQ OQ
COMPOUND DESCRIPTOR : Reproductive Effector
Hormone
SYNONYMS/TRADE NAMES :
* 3-beta,17-Dihydroxypregn-5-en-20-one
* 17-Hydroxypregnenolone
* 17-alpha-Hydroxypregnenolone
* Pregn-5-en-20-one, 3,17-dihydroxy-, (3-beta)-
*** HEALTH HAZARD DATA ***
** REPRODUCTIVE DATA **
TYPE OF TEST : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE : Intramuscular
SPECIES OBSERVED : Rodent - rat
DOSE : 99600 ug/kg
SEX/DURATION : male 48 day(s) pre-mating
TOXIC EFFECTS :
Reproductive - Paternal Effects - spermatogenesis (incl. genetic material,
sperm morphology, motility, and count)
Reproductive - Paternal Effects - testes, epididymis, sperm duct
Reproductive - Paternal Effects - prostate, seminal vesicle, Cowper's gland,
accessory glands
REFERENCE :
IJEBA6 Indian Journal of Experimental Biology. (Publications & Information
Directorate, CSIR, Hillside Rd., New Delhi 110 012, India) V.1- 1963-
Volume(issue)/page/year: 5,45,1967
TYPE OF TEST : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE : Intramuscular
SPECIES OBSERVED : Rodent - rat
DOSE : 96 mg/kg
SEX/DURATION : male 48 day(s) pre-mating
TOXIC EFFECTS :
Reproductive - Fertility - mating performance (e.g. # sperm positive females
per # females mated; # copulations per # estrus cycles)
REFERENCE :
IJEBA6 Indian Journal of Experimental Biology. (Publications & Information
Directorate, CSIR, Hillside Rd., New Delhi 110 012, India) V.1- 1963-
Volume(issue)/page/year: 11,484,1973
*** END OF RECORD ***