*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : TU5535000
CHEMICAL NAME           : 5-alpha-Pregn-17(20)-en-21-oic acid,
                          3-beta,16-beta-dihydroxy-11-oxo-, gamma-lactone
CAS REGISTRY NUMBER     : 337-67-7
LAST UPDATED            : 199709
DATA ITEMS CITED        : 1
MOLECULAR FORMULA       : C21-H28-O4
MOLECULAR WEIGHT        : 344.49
WISWESSER LINE NOTATION : T F5 E5 B666 CV HVO JH&TTTTJ A1 E1 P1 RQ
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * 3-beta,16-beta-Dihydroxy-11-oxo-5-alpha-pregn-17(20)-en-21-oic acid,  
   gamma-lactone
   * Pregn-17(20)-en-21-oic acid, 3,16-dihydroxy-11-oxo-, gamma-lactone,  
   (3-beta,5-alpha,16-beta)-
   * U 18317
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 115 mg/kg
TOXIC EFFECTS :
   Tumorigenic - active as anti-cancer agent
REFERENCE :
   JMCMAR Journal of Medicinal Chemistry.  (American Chemical Soc.,
   Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC
   20037)  V.6-    1963-  Volume(issue)/page/year: 7,348,1964
 
                            *** END OF RECORD ***