*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : TU5010147
CHEMICAL NAME           : Preg-4-ene-3,20-dione,
                          21-(3-carboxy-1-oxopropoxy)-11,17-dihydroxy-,
                          (11-beta)-
CAS REGISTRY NUMBER     : 2203-97-6
LAST UPDATED            : 199504
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C25-H34-O8
MOLECULAR WEIGHT        : 462.59
SYNONYMS/TRADE NAMES :
   *   (11-beta)-21-(3-Carboxy-1-oxopropoxy)-11,17-dihydroxypreg-4-ene-3,20-dio
     ne
   * Cortisol hemisuccinate
   * Cortisol 21-hemisuccinate
   * Cortisol, 21-(hydrogen succinate)
   * Cortisol, hydrogen succinate
   * Cortisol succinate
   * Hydrocortisone hemisuccinate
   * Hydrocortisone 21-hemisuccinate
   * Hydrocortisone hydrogen succinate
   * Hydrocortisone succinate
   * Hydrocortisone 21-succinate
   * Saxizon
 
                       *** HEALTH HAZARD DATA ***
 
                 ** OTHER MULTIPLE DOSE TOXICITY DATA **
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 4200 mg/kg/10W-C
TOXIC EFFECTS :
   Immunological Including Allergic - decrease in humoral immune response
REFERENCE :
   BECTA6 Bulletin of Environmental Contamination and Toxicology.
   (Springer-Verlag New York, Inc., Service Center, 44 Hartz Way, Secaucus, NJ
   07094)  V.1-    1966-  Volume(issue)/page/year: 41,523,1988

         *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA ***

NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA :
   NOES - National Occupational Exposure Survey (1983)
     NOES Hazard Code - X4704
       No. of Facilities: 114 (estimated)
       No. of Industries: 1
       No. of Occupations: 5
       No. of Employees: 16945 (estimated)
       No. of Female Employees: 15681 (estimated)

 
                            *** END OF RECORD ***