*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : TU4818500
CHEMICAL NAME           : Pregn-5-ene-18,20-alpha-diol, 3-beta-(methylamino)-,
                          hydrochloride
CAS REGISTRY NUMBER     : 29847-81-2
LAST UPDATED            : 199109
DATA ITEMS CITED        : 3
MOLECULAR FORMULA       : C22-H37-N-O2.Cl-H
MOLECULAR WEIGHT        : 384.06
SYNONYMS/TRADE NAMES :
   * 18,20-Dihydroxy-3-beta-methylaminopregn-5-ene hydrochloride
   * 3-beta-Methylaminopregn-5-ene-18,20-diol hydrochloride
   * Paravallarinol hydrochloride
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 1 gm/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   CHTPBA Chimica Therapeutica.  (Paris, France)  V.1-8, 1965-73.  For
   publisher information, see EJMCA5.  Volume(issue)/page/year: 5,129,1970
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 300 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   CHTPBA Chimica Therapeutica.  (Paris, France)  V.1-8, 1965-73.  For
   publisher information, see EJMCA5.  Volume(issue)/page/year: 5,129,1970
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 45 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   CHTPBA Chimica Therapeutica.  (Paris, France)  V.1-8, 1965-73.  For
   publisher information, see EJMCA5.  Volume(issue)/page/year: 5,129,1970
 
                            *** END OF RECORD ***