*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : TU4817000
CHEMICAL NAME           : Pregn-5-ene-18,20-alpha-diol, 3-beta-(methylamino)-
CAS REGISTRY NUMBER     : 17083-11-3
LAST UPDATED            : 198702
DATA ITEMS CITED        : 3
MOLECULAR FORMULA       : C22-H37-N-O2
MOLECULAR WEIGHT        : 347.60
COMPOUND DESCRIPTOR     : Drug
                          Hormone
SYNONYMS/TRADE NAMES :
   * (20S)-3-beta-N Methyl-amino-18,20-dihydroxypregna-5-ene
   * Paravallarinol
   * Pregn-5-ene-18,20-diol, 3-(methylamino)-, (3-beta,20S)-
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 1150 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   THERAP Therapie.  (Doin, Editeurs, 8, Place de l'Odeon, F-75006 Paris,
   France)  V.1-    1946-  Volume(issue)/page/year: 25,795,1970
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 200 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   THERAP Therapie.  (Doin, Editeurs, 8, Place de l'Odeon, F-75006 Paris,
   France)  V.1-    1946-  Volume(issue)/page/year: 25,795,1970
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 67 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   THERAP Therapie.  (Doin, Editeurs, 8, Place de l'Odeon, F-75006 Paris,
   France)  V.1-    1946-  Volume(issue)/page/year: 25,795,1970
 
                            *** END OF RECORD ***