*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : TU4157072
CHEMICAL NAME           : 17-alpha-Pregna-2,4-dien-20-yno(2,3-d)isoxazol-17-ol,
                          and 17-beta-hydroxy-17-methylandrost- 4-en-3-one
LAST UPDATED            : 198910
DATA ITEMS CITED        : 1
MOLECULAR FORMULA       : C22-H28-N-O2.C20-H30-O2
MOLECULAR WEIGHT        : 641.01
COMPOUND DESCRIPTOR     : Reproductive Effector
                          Human
                          Hormone
SYNONYMS/TRADE NAMES :
   * Danazol and methyltestosterone
   * Methyltestosterone and danazol
 
                       *** HEALTH HAZARD DATA ***
 
                          ** REPRODUCTIVE DATA **
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Unreported
SPECIES OBSERVED        : Human - man
DOSE                    : 750 mg/kg
SEX/DURATION            : male 84 day(s) pre-mating
TOXIC EFFECTS :
   Reproductive - Paternal Effects - spermatogenesis (incl. genetic material,
   sperm morphology, motility, and count)
REFERENCE :
   CCPTAY Contraception.  (Geron-X, Inc., POB 1108, Los Altos, CA 94022)  V.1-
   1970-  Volume(issue)/page/year: 12,437,1975
 
                            *** END OF RECORD ***