*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : TU4156900
CHEMICAL NAME           : Pregna-4,6-dien-20-one,
                          3-beta,17-dihydroxy-6-methyl-, diacetate
CAS REGISTRY NUMBER     : 3116-07-2
LAST UPDATED            : 199207
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C26-H36-O5
MOLECULAR WEIGHT        : 428.62
COMPOUND DESCRIPTOR     : Drug
                          Reproductive Effector
SYNONYMS/TRADE NAMES :
   * Acetomepregenol
   * Diamol
   * Mepregenol diacetate
   * Pregna-4,6-dien-20-one, 3,17-bis(acetyloxy)-6-methyl-, (3-beta)-
 
                       *** HEALTH HAZARD DATA ***
 
                 ** OTHER MULTIPLE DOSE TOXICITY DATA **
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 90 mg/kg/60D-I
TOXIC EFFECTS :
   Gastrointestinal - changes in pancreatic weight
   Endocrine - changes in pituitary weight
   Related to Chronic Data - changes in ovarian weight
REFERENCE :
   FATOAO Farmakologiya i Toksikologiya (Moscow).  For English translation, see
   PHTXA6 and RPTOAN. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.2-   
   1939-  Volume(issue)/page/year: 54(2),43,1991
 
                          ** REPRODUCTIVE DATA **
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE                    : 1500 ug/kg
SEX/DURATION            : female 11 day(s) after conception
TOXIC EFFECTS :
   Reproductive - Fertility - post-implantation mortality (e.g. dead and/or
   resorbed implants per total number of implants)
REFERENCE :
   FATOAO Farmakologiya i Toksikologiya (Moscow).  For English translation, see
   PHTXA6 and RPTOAN. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.2-   
   1939-  Volume(issue)/page/year: 54(2),43,1991
 
                            *** END OF RECORD ***