*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : TU3751000
CHEMICAL NAME           : Pregna-1,4-diene-3,20-dione,
                          6-alpha-chloro-17-alpha-hydroxy-, acetate (ester)
CAS REGISTRY NUMBER     : 151-69-9
LAST UPDATED            : 198910
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C23-H29-Cl-O4
MOLECULAR WEIGHT        : 404.97
COMPOUND DESCRIPTOR     : Reproductive Effector
                          Hormone
SYNONYMS/TRADE NAMES :
   * 6-alpha-Chloro-delta(sup 1)-dehydro-17-alpha-acetoxyprogesterone
   * 6-alpha-Chloro-17-alpha-hydroxypregna-1,4-diene-3,20-dione acetate  
   (ester)
   * Cismadinone acetate
 
                       *** HEALTH HAZARD DATA ***
 
                          ** REPRODUCTIVE DATA **
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rabbit
DOSE                    : 78500 ng/kg
SEX/DURATION            : female 1 day(s) pre-mating
TOXIC EFFECTS :
   Reproductive - Fertility - other measures of fertility
REFERENCE :
   ACEDAB Acta Endocrinologica, Supplementum (Copenhagen).  (Periodica,
   Skolegade 12 E, DK-2500 Valby, Denmark)  No.1-    1948-
   Volume(issue)/page/year: 73,17,1963
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - rabbit
DOSE                    : 37500 ng/kg
SEX/DURATION            : female 1 day(s) pre-mating
TOXIC EFFECTS :
   Reproductive - Fertility - mating performance (e.g. # sperm positive females
   per # females mated; # copulations per # estrus cycles)
   Reproductive - Fertility - other measures of fertility
REFERENCE :
   ACEDAB Acta Endocrinologica, Supplementum (Copenhagen).  (Periodica,
   Skolegade 12 E, DK-2500 Valby, Denmark)  No.1-    1948-
   Volume(issue)/page/year: 73,3,1963
 
                            *** END OF RECORD ***