*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : TP8750000
CHEMICAL NAME           : Podophyllic acid
CAS REGISTRY NUMBER     : 1853-37-8
LAST UPDATED            : 199112
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C22-H24-O9
MOLECULAR WEIGHT        : 432.46
WISWESSER LINE NOTATION : T C566 DO FO EH&&TJ JQ K1Q LVQ MR CO1 DO1 EO1
COMPOUND DESCRIPTOR     : Natural Product
SYNONYMS/TRADE NAMES :
   * Diaethyl-(2-chlor-1-(2,4-dichlorphenyl))-vinyl-phosphat
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 899 mg/kg
TOXIC EFFECTS :
   Behavioral - excitement
   Behavioral - muscle weakness
   Lungs, Thorax, or Respiration - dyspnea
REFERENCE :
   PSEBAA Proceedings of the Society for Experimental Biology and Medicine.
   (Academic Press, Inc., 1 E. First St., Duluth, MN 55802)  V.1-    1903/04-
   Volume(issue)/page/year: 77,269,1951
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 700 mg/kg
TOXIC EFFECTS :
   Behavioral - excitement
   Behavioral - muscle weakness
   Lungs, Thorax, or Respiration - dyspnea
REFERENCE :
   PSEBAA Proceedings of the Society for Experimental Biology and Medicine.
   (Academic Press, Inc., 1 E. First St., Duluth, MN 55802)  V.1-    1903/04-
   Volume(issue)/page/year: 77,269,1951
 
                            *** END OF RECORD ***