*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : TP8700000
CHEMICAL NAME           : Podocarpa-8,11,13-trien-15-amide,
                          N,N-bis(2-chloroethyl)-13-isopropyl-
CAS REGISTRY NUMBER     : 40713-30-2
LAST UPDATED            : 199803
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C24-H39-Cl2-N-O
MOLECULAR WEIGHT        : 428.54
WISWESSER LINE NOTATION : L B666&TTJ A1 EY1&1 KVN2G2G K1
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * Abietamide, N,N-bis(2-chloroethyl)-
   * N,N-Bis(2-chloroethyl)abietamide
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 30 mg/kg
TOXIC EFFECTS :
   Tumorigenic - active as anti-cancer agent
REFERENCE :
   PCJOAU Pharmaceutical Chemistry Journal (English Translation).  Translation
   of KHFZAN. (Plenum Pub. Corp., 233 Spring St., New York, NY 10013)  No.1-
   1967-  Volume(issue)/page/year: 6,647,1972
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 80 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   PCJOAU Pharmaceutical Chemistry Journal (English Translation).  Translation
   of KHFZAN. (Plenum Pub. Corp., 233 Spring St., New York, NY 10013)  No.1-
   1967-  Volume(issue)/page/year: 6,647,1972
 
                            *** END OF RECORD ***