*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : TP8650000
CHEMICAL NAME           : 8-beta-Podocarpane-delta(sup 13,alpha)-acetic acid,
                          3-beta-hydroxy-14-methyl-7-oxo-,
                          2-(dimethylamino)ethyl ester,
                          3-hydroxy-3-methylbutyrate (ester), hydrochloride
CAS REGISTRY NUMBER     : 22149-23-1
LAST UPDATED            : 198706
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C29-H47-N-O6.Cl-H
MOLECULAR WEIGHT        : 542.23
WISWESSER LINE NOTATION : L B666 EY HVTJ A1 EU1VO2N1&1 F1 K1 K1 LOV1XQ1&1 &GH
SYNONYMS/TRADE NAMES :
   * Coumingine hydrochloride
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Mammal - cat
DOSE/DURATION           : 108 ug/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   JPETAB Journal of Pharmacology and Experimental Therapeutics.  (Williams &
   Wilkins Co., 428 E. Preston St., Baltimore, MD 21202)  V.1-    1909/10-
   Volume(issue)/page/year: 74,223,1942
 
TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - guinea pig
DOSE/DURATION           : 1770 ug/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   APSXAS Acta Pharmaceutica Suecica.  (Apotekarsocieteten-Farmacevtiska
   Foereningen, Box 1136, S-111, 81 Stockholm, Sweden)  V.1-    1964-
   Volume(issue)/page/year: 13,35,1976
 
                            *** END OF RECORD ***