*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : TQ3500000
CHEMICAL NAME           : Polyethylene glycol
CAS REGISTRY NUMBER     : 25322-68-3
OTHER CAS REGISTRY NOS. : 88747-22-2
LAST UPDATED            : 199710
DATA ITEMS CITED        : 12
MOLECULAR FORMULA       : (C2-H4-O)n-H2-O
WISWESSER LINE NOTATION : /*O2*/
COMPOUND DESCRIPTOR     : Mutagen
                          Primary Irritant
SYNONYMS/TRADE NAMES :
   * Alkapol peg-200
   * Alkapol peg-300
   * Alkapol peg-600
   * Alkapol peg-6000
   * Alkapol peg-8000
   * Carbowax
   * Carbowax peg 3350
   * alpha-Hydro-omega-hydroxypoly(oxy-1,2-ethanediyl)
   * Jorchem 400 ML
   * Lutrol
   * PEG 3350
   * Pluracol E-200
   * Pluracol E-300
   * Pluracol E-400
   * Pluracol E-600
   * Pluracol E-1500
   * Pluracol E-4000
   * Pluracol E-6000
   * Pluracol P-410
   * Pluracol P-710
   * Pluracol P-1010
   * Pluracol P-2010
   * Pluracol P-3010
   * Pluracol P-4010
   * Poly(ethylene oxide)
   * Poly-G series
   * Polyox
   * Poly(oxy-1,2-ethanediyl), alpha-hydro-omega-hydroxy-
 
                       *** HEALTH HAZARD DATA ***
 
                      ** SKIN/EYE IRRITATION DATA **
 
TYPE OF TEST            : Standard Draize test
ROUTE OF EXPOSURE       : Administration onto the skin
SPECIES OBSERVED        : Rodent - rabbit
DOSE/DURATION           : 500 mg/24H
REACTION SEVERITY       : Mild
REFERENCE :
   28ZPAK "Sbornik Vysledku Toxixologickeho Vysetreni Latek A Pripravku,"
   Marhold, J.V., Institut Pro Vychovu Vedoucicn Pracovniku Chemickeho Prumyclu
   Praha, Czechoslovakia, 1972  Volume(issue)/page/year: -,255,1972
 
TYPE OF TEST            : Standard Draize test
ROUTE OF EXPOSURE       : Administration into the eye
SPECIES OBSERVED        : Rodent - rabbit
DOSE/DURATION           : 500 mg/24H
REACTION SEVERITY       : Mild
REFERENCE :
   28ZPAK "Sbornik Vysledku Toxixologickeho Vysetreni Latek A Pripravku,"
   Marhold, J.V., Institut Pro Vychovu Vedoucicn Pracovniku Chemickeho Prumyclu
   Praha, Czechoslovakia, 1972  Volume(issue)/page/year: -,255,1972
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 22 gm/kg
TOXIC EFFECTS :
   Cardiac - arrhythmias (including changes in conduction)
   Vascular - BP lowering not characterized in autonomic section
   Kidney, Ureter, Bladder - hematuria
REFERENCE :
   ARZNAD Arzneimittel-Forschung. Drug Research.  (Editio Cantor Verlag,
   Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.)  V.1-    1951-
   Volume(issue)/page/year: 23,1087,1973
 
                 ** OTHER MULTIPLE DOSE TOXICITY DATA **
 
TYPE OF TEST            : TCLo - Lowest published toxic concentration
ROUTE OF EXPOSURE       : Inhalation
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 567 mg/m3/6H/2W-I
TOXIC EFFECTS :
   Lungs, Thorax, or Respiration - changes in lung weight
   Nutritional and Gross Metabolic - weight loss or decreased weight gain
REFERENCE :
   DCTODJ Drug and Chemical Toxicology.  (Marcel Dekker, 270 Madison Ave., New
   York, NY 10016) V.1-    1977/78-  Volume(issue)/page/year: 12,39,1989

         *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA ***

NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA :
   NOHS - National Occupational Hazard Survey (1974)
     NOHS Hazard Code - T0788
       No. of Facilities: 60 (estimated)
       No. of Industries: 4
       No. of Occupations: 6
       No. of Employees: 1675 (estimated)
   
   NOHS - National Occupational Hazard Survey (1974)
     NOHS Hazard Code - 80189
       No. of Facilities: 34023 (estimated)
       No. of Industries: 237
       No. of Occupations: 159
       No. of Employees: 487377 (estimated)
   
   NOES - National Occupational Exposure Survey (1983)
     NOES Hazard Code - X7669
       No. of Facilities: 37662 (estimated)
       No. of Industries: 225
       No. of Occupations: 183
       No. of Employees: 1335913 (estimated)
       No. of Female Employees: 861947 (estimated)

                          *** STATUS IN U.S. ***
 
   EPA GENETOX PROGRAM 1988, Inconclusive: E coli polA without S9
   
   EPA TSCA Section 8(b) CHEMICAL INVENTORY
   
   EPA TSCA Section 8(d) unpublished health/safety studies
   
   EPA TSCA Section 8(e) Risk Notification, 8EHQ-0892-8800
   
   EPA TSCA TEST SUBMISSION (TSCATS) DATA BASE, JUNE 1998

 
                            *** END OF RECORD ***