*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : TQ2700000
CHEMICAL NAME           : Polydimethylsiloxane rubber
CAS REGISTRY NUMBER     : 63394-02-5
LAST UPDATED            : 199504
DATA ITEMS CITED        : 4
COMPOUND DESCRIPTOR     : Tumorigen
SYNONYMS/TRADE NAMES :
   * Dow corning 790
   * Dow corning 795
   * Dow corning 999
   * Dow corning 3110
   * Dow corning 3112
   * Dow corning 3120
   * Dow corning 3-5000 cornstruction coating
   * Polysilicone
   * Silastic
   * Silastic 1603
   * Silastic rtv 1890 protective sealer
   * Silastic silicone rubber
   * Silicone rubber
 
                       *** HEALTH HAZARD DATA ***
 
                          ** TUMORIGENIC DATA **
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Implant
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 1500 mg/kg
TOXIC EFFECTS :
   Tumorigenic - Carcinogenic by RTECS criteria
   Cardiac - tumors
REFERENCE :
   AMPLAO AMA Archives of Pathology.  (Chicago, IL)  V.50(4)-69, 1950-60.  For
   publisher information, see APLMAS.  Volume(issue)/page/year: 67,589,1959
 
TYPE OF TEST            : TD - Toxic dose (other than lowest)
ROUTE OF EXPOSURE       : Implant
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 900 mg/kg
TOXIC EFFECTS :
   Tumorigenic - equivocal tumorigenic agent by RTECS criteria
   Kidney, Ureter, Bladder - tumors
   Blood - lymphoma, including Hodgkin's disease
REFERENCE :
   JNCIAM Journal of the National Cancer Institute.  (Washington, DC)  V.1-60,
   1940-78.  For publisher information, see JJIND8.  Volume(issue)/page/year:
   33,1005,1964

         *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA ***

NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA :
   NOHS - National Occupational Hazard Survey (1974)
     NOHS Hazard Code - 80616
       No. of Facilities: 771 (estimated)
       No. of Industries: 23
       No. of Occupations: 23
       No. of Employees: 9102 (estimated)
   
   NOES - National Occupational Exposure Survey (1983)
     NOES Hazard Code - 80616
       No. of Facilities: 220 (estimated)
       No. of Industries: 5
       No. of Occupations: 10
       No. of Employees: 6511 (estimated)
       No. of Female Employees: 3038 (estimated)

 
                            *** END OF RECORD ***