*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : TP2485802
CHEMICAL NAME           : Platinum(IV), diamminetetrachloro-, (E)-
CAS REGISTRY NUMBER     : 16893-06-4
LAST UPDATED            : 199410
DATA ITEMS CITED        : 4
MOLECULAR FORMULA       : Cl4-H6-N2-Pt
MOLECULAR WEIGHT        : 370.97
COMPOUND DESCRIPTOR     : Mutagen
SYNONYMS/TRADE NAMES :
   * trans-Tetrachlorodiammine platinum(IV)
 
                       *** HEALTH HAZARD DATA ***
 
                            ** MUTATION DATA **
 
TYPE OF TEST            : Mutation in microorganisms
TEST SYSTEM             : Bacteria - Salmonella typhimurium
DOSE/DURATION           : 30 ug/plate
REFERENCE :
   MUREAV Mutation Research.  (Elsevier Science Pub. B.V., POB 211, 1000 AE
   Amsterdam, Netherlands) V.1-    1964-  Volume(issue)/page/year: 95,79,1982
 
TYPE OF TEST            : Phage inhibition capacity
TEST SYSTEM             : Bacteria - Escherichia coli
DOSE/DURATION           : 50 umol/L
REFERENCE :
   CBINA8 Chemico-Biological Interactions.  (Elsevier Scientific Pub. Ireland
   Ltd., POB 85, Limerick, Ireland)  V.1-    1969-  Volume(issue)/page/year:
   4,66,1971/1972
 
TYPE OF TEST            : DNA adduct
TEST SYSTEM             : Rodent - hamster Ovary
DOSE/DURATION           : 1 umol/L
REFERENCE :
   CNREA8 Cancer Research. (Public Ledger Building, Suit 816, 6th & Chestnut
   Sts., Philadelphia, PA 19106)  V.1-    1941-  Volume(issue)/page/year:
   44,2043,1984
 
TYPE OF TEST            : DNA adduct
TEST SYSTEM             : Mammal - species unspecified Lymphocyte
DOSE/DURATION           : 50 umol/L
REFERENCE :
   CBINA8 Chemico-Biological Interactions.  (Elsevier Scientific Pub. Ireland
   Ltd., POB 85, Limerick, Ireland)  V.1-    1969-  Volume(issue)/page/year:
   10,27,1975
 
                            *** END OF RECORD ***