*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : TP2275850
CHEMICAL NAME           : Platinum,
                          (1,2-cyclohexanediamine-N,N')(ethanedioato(2-)-O,O')-
                          , (SP-4-2-(1R-trans))-
CAS REGISTRY NUMBER     : 61825-94-3
LAST UPDATED            : 199706
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C8-H14-N2-O4-Pt
MOLECULAR WEIGHT        : 397.33
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * 1-OHP
   * Oxalato(1R,2R-cyclohexanediammine)platinum(II)
   * Oxalatoplatin
   * Oxalatoplatinum
   * Oxaliplatin
   * Oxaliplatino
   * RP 54780
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 14300 ug/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   DRFUD4 Drugs of the Future.  (J.R. Prous, S.A., Apartado de Correos 540,
   08080 Barcelona, Spain) V.1-    1975/76-  Volume(issue)/page/year:
   14,529,1989
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 19800 ug/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   DRFUD4 Drugs of the Future.  (J.R. Prous, S.A., Apartado de Correos 540,
   08080 Barcelona, Spain) V.1-    1975/76-  Volume(issue)/page/year:
   14,529,1989
 
                            *** END OF RECORD ***