*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : TP2275814
CHEMICAL NAME           : Platinum,
                          (1,1-cyclobutanedicarboxylato(2-))(2-pyrrolidinemetha
                          namine-N(sup alpha),N(sup 1))-,(SP-4-3-(S))-
CAS REGISTRY NUMBER     : 103775-74-2
LAST UPDATED            : 199506
DATA ITEMS CITED        : 1
MOLECULAR FORMULA       : C11-H18-N2-O4-Pt
MOLECULAR WEIGHT        : 437.40
SYNONYMS/TRADE NAMES :
   * DWA 2114S
 
                       *** HEALTH HAZARD DATA ***
 
                 ** OTHER MULTIPLE DOSE TOXICITY DATA **
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 70 mg/kg/2W-I
TOXIC EFFECTS :
   Cardiac - changes in heart weight
   Endocrine - changes in spleen weight
   Nutritional and Gross Metabolic - weight loss or decreased weight gain
REFERENCE :
   YACHDS Yakuri to Chiryo.  Pharmacology and Therapeutics.  (Raifu Saiensu
   Shuppan K.K., 2-5-13, Yaesu, Chuo-ku, Tokyo 104, Japan)  V.1-    1972-
   Volume(issue)/page/year: 20(Suppl 3),S721,1992
 
                            *** END OF RECORD ***