*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : TP2261000
CHEMICAL NAME           : Platinum (IV),
                          bis(1,3-propanediammine)dichlorodihydroxo-, cis-
LAST UPDATED            : 198309
DATA ITEMS CITED        : 1
MOLECULAR FORMULA       : C6-H22-Cl2-N2-O2-Pt
MOLECULAR WEIGHT        : 420.29
WISWESSER LINE NOTATION : Z3Z 2 &Q-PT-QGG -C
SYNONYMS/TRADE NAMES :
   * cis-Bis(1,3-propanediammine)dichlorodihydroxoplatinum (IV)
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 23 mg/kg
TOXIC EFFECTS :
   Kidney, Ureter, Bladder - other changes
   Tumorigenic - active as anti-cancer agent
REFERENCE :
   CBINA8 Chemico-Biological Interactions.  (Elsevier Scientific Pub. Ireland
   Ltd., POB 85, Limerick, Ireland)  V.1-    1969-  Volume(issue)/page/year:
   11,145,1975
 
                            *** END OF RECORD ***