*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : TP2225000
CHEMICAL NAME           : Platinum (II),
                          bis(1-(2-hydroxyethyl)aziridine)dichloro-, (Z)-
CAS REGISTRY NUMBER     : 63976-08-9
LAST UPDATED            : 199506
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C8-H20-Cl2-N2-O2-Pt
MOLECULAR WEIGHT        : 442.29
WISWESSER LINE NOTATION : T3NTJ A2Q 2 &G-PT-G -Z
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * cis-Bis(1-(2-hydroxyethyl)aziridine)dichloroplatinum(II)
   * cis-Dichlorobis-N-(2-hydroxyethyl)ethyleneimineplatinum (II)
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 90 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   CBINA8 Chemico-Biological Interactions.  (Elsevier Scientific Pub. Ireland
   Ltd., POB 85, Limerick, Ireland)  V.1-    1969-  Volume(issue)/page/year:
   5,415,1972

                              *** REVIEWS ***
 
   TOXICOLOGY REVIEW
   JPMSAE Journal of Pharmaceutical Sciences.  (American Pharmaceutical Assoc.,
   2215 Constitution Ave., NW, Washington, DC 20037)  V.50-    1961-
   Volume(issue)/page/year: 65,315,1976

 
                            *** END OF RECORD ***