*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : TP2197000
CHEMICAL NAME           : Platinum (II), bis(cycloheptylammine)dichloro-, cis-
CAS REGISTRY NUMBER     : 41637-13-2
LAST UPDATED            : 199201
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C14-H30-Cl2-N2-Pt
MOLECULAR WEIGHT        : 492.45
WISWESSER LINE NOTATION : L7TJ AZ 2 &G-PT-G -C
SYNONYMS/TRADE NAMES :
   * cis-Bis(cycloheptylammine)dichloroplatinum(II)
   * cis-Dichlorobis(cycloheptylammine)platinum(II)
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 625 mg/kg
TOXIC EFFECTS :
   Kidney, Ureter, Bladder - other changes in urine composition
   Blood - changes in bone marrow (not otherwise specified)
   Biochemical - Enzyme inhibition, induction, or change in blood or tissue
   levels - dehydrogenases
REFERENCE :
   JPMSAE Journal of Pharmaceutical Sciences.  (American Pharmaceutical Assoc.,
   2215 Constitution Ave., NW, Washington, DC 20037)  V.50-    1961-
   Volume(issue)/page/year: 65,315,1976
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Unreported
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : >625 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   RRCRBU Recent Results in Cancer Research.  (Springer-Verlag New York, Inc.,
   Service Center, 44 Hartz Way, Secaucus, NJ 07094)  V.1-    1965-
   Volume(issue)/page/year: 48,12,1974
 
                            *** END OF RECORD ***