*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : TP2195000
CHEMICAL NAME           : Platinum (II), bis(cyclobutylammine)dichloro-, cis-
CAS REGISTRY NUMBER     : 38780-37-9
LAST UPDATED            : 199410
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C8-H18-Cl2-N2-Pt
MOLECULAR WEIGHT        : 408.27
WISWESSER LINE NOTATION : L4TJ AZ 2 &G-PT-G -C
COMPOUND DESCRIPTOR     : Drug
                          Mutagen
SYNONYMS/TRADE NAMES :
   * cis-Bis(cyclobutylammine)dichloroplatinum(II)
   * cis-Dichlorobis(cyclobutylammine)platinum(II)
   * cis-Dicyclobutylamminedichloroplatinum (II)
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 90 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   CBINA8 Chemico-Biological Interactions.  (Elsevier Scientific Pub. Ireland
   Ltd., POB 85, Limerick, Ireland)  V.1-    1969-  Volume(issue)/page/year:
   5,415,1972
 
                            ** MUTATION DATA **
 
TYPE OF TEST            : Mutation in microorganisms
TEST SYSTEM             : Bacteria - Salmonella typhimurium
DOSE/DURATION           : 1 umol/plate
REFERENCE :
   CBINA8 Chemico-Biological Interactions.  (Elsevier Scientific Pub. Ireland
   Ltd., POB 85, Limerick, Ireland)  V.1-    1969-  Volume(issue)/page/year:
   26,179,1979
 
                            *** END OF RECORD ***