*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : TN7700000
CHEMICAL NAME           : 4-Piperidinol,
                          1-(3-(2-methoxyphenothiazin-10-yl)-2-methylpropyl)-,
                          hydrochloride
LAST UPDATED            : 199009
DATA ITEMS CITED        : 4
MOLECULAR FORMULA       : C22-H28-N2-O2-S.Cl-H
MOLECULAR WEIGHT        : 421.04
WISWESSER LINE NOTATION : T C666 BN ISJ EO1 B1Y1&1- AT6NTJ DQ &GH
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * AN 1317 hydrochloride
   * 1317 AN hydrochloride
   * Leptryl hydrochloride
   * 2-Methoxy-10-(3-(4-hydroxypiperidino)-2-methylpropyl)phenothiazine  
   hydrochloride
   * 2-Methoxy-10-(2-methyl-3-(4-hydroxypiperidino)propyl)phenothiazine  
   hydrochloride
   * 1-(3-(2-Methoxyphenothiazin-10-yl)-2-methylpropyl)-4-piperidinol  
   hydrochloride
   * Perimetazine hydrochloride
   * Perimethazine hydrochloride
   * RP 9159 hydrochloride
   * 9159 RP hydrochloride
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 310 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   CRSBAW Comptes Rendus des Seances de la Societe de Biologie et de Ses
   Filiales.  (SPPIF, B.P.22, F-41353 Vineuil, France)  V.1-    1849-
   Volume(issue)/page/year: 160,1852,1966
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 140 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   CRSBAW Comptes Rendus des Seances de la Societe de Biologie et de Ses
   Filiales.  (SPPIF, B.P.22, F-41353 Vineuil, France)  V.1-    1849-
   Volume(issue)/page/year: 160,1852,1966
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 330 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   CRSBAW Comptes Rendus des Seances de la Societe de Biologie et de Ses
   Filiales.  (SPPIF, B.P.22, F-41353 Vineuil, France)  V.1-    1849-
   Volume(issue)/page/year: 160,1852,1966
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 115 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   CRSBAW Comptes Rendus des Seances de la Societe de Biologie et de Ses
   Filiales.  (SPPIF, B.P.22, F-41353 Vineuil, France)  V.1-    1849-
   Volume(issue)/page/year: 160,1852,1966
 
                            *** END OF RECORD ***