*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : TN3703000
CHEMICAL NAME           : 1-Piperidinepropanol, alpha-(5-phenyl-3-isoxazolyl)-,
                          monohydrochloride
CAS REGISTRY NUMBER     : 13586-52-2
LAST UPDATED            : 199007
DATA ITEMS CITED        : 1
MOLECULAR FORMULA       : C17-H22-N2-O2.Cl-H
MOLECULAR WEIGHT        : 322.87
WISWESSER LINE NOTATION : T6NTJ A2YQ- ET5NOJ CR &GH
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * 3-(1-Hydroxy-3-piperidinopropyl)-5-phenylisoxazole hydrochloride
   * Isoxazole, 3-(1-hydroxy-3-piperidinopropyl)-5-phenyl-, hydrochloride
   * 3-Isoxazolemethanol, 5-phenyl-, alpha-(2-piperidinoethyl)-, hydrochloride
   * 1-Propanol, (1-(5-phenyl-3-isoxazolyl))-3-piperidino-, monohydrochloride
   * 1-Propanol, 3-piperidino-1-(5-phenyl-3-isoxazolyl)-, hydrochloride
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 500 mg/kg
TOXIC EFFECTS :
   Behavioral - analgesia
   Nutritional and Gross Metabolic - body temperature decrease
   Biochemical - Metabolism (Intermediary) - effect on inflammation or
   mediation of inflammation
REFERENCE :
   JMCMAR Journal of Medicinal Chemistry.  (American Chemical Soc.,
   Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC
   20037)  V.6-    1963-  Volume(issue)/page/year: 10,411,1967
 
                            *** END OF RECORD ***